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Neoadjuvant chemotherapy combined with Bevacizumab shows promise for HER2 negative breast cancer but may lead to various side effects that patients should be aware of.
Q: What is Neoadjuvant Chemotherapy?
- Neoadjuvant chemotherapy is treatment given before surgery to shrink tumors.
- Aim: To increase the chances of breast-conserving surgery.
Q: What is Bevacizumab?
- Bevacizumab is a monoclonal antibody that inhibits angiogenesis.
- Aim: To reduce tumor blood supply and help chemotherapy work better.
Q: What are the potential side effects of Neoadjuvant Chemotherapy?
- Common side effects include:
- Nausea and Vomiting
- Fatigue
- Hair Loss
- Low Blood Cell Counts (anemia, neutropenia)
- Mouth Sores
- Less Common but Serious Effects:
- Heart Problems
- Liver Toxicity
Q: What are the potential side effects of Bevacizumab?
- Common side effects include:
- High Blood Pressure
- Fatigue
- Gastrointestinal Perforation
- Delayed Wound Healing
- Less common but severe effects:
- Risk of Hemorrhage
- Cardiovascular Events
Statistical Overview of Side Effects
Side Effect | Incidence Rate (%) |
---|---|
Nausea | 70 |
Fatigue | 65 |
Hypertension (Bevacizumab) | 30 |
Heart Problems | 5-10 |
Gastrointestinal Perforation | 1-5 |
Mind Map of Side Effects
– Neoadjuvant Chemotherapy – Nausea – Fatigue – Hair Loss – Blood Cell Decrease – Mouth Sores – Serious: Heart Problems, Liver Toxicity – Bevacizumab – High Blood Pressure – Fatigue – Gastrointestinal Issues – Serious: Hemorrhage Risk, Cardiovascular Events
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