What are the potential side effects of Neoadjuvant Chemotherapy and Bevacizumab for patients with HER2 Negative Breast Cancer?
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    What are the potential side effects of Neoadjuvant Chemotherapy and Bevacizumab for patients with HER2 Negative Breast Cancer?
    Updated:17/04/2024
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    MoonbeamDreamer
    Updated:08/05/2024

    Neoadjuvant chemotherapy combined with Bevacizumab shows promise for HER2 negative breast cancer but may lead to various side effects that patients should be aware of.

    Q: What is Neoadjuvant Chemotherapy?
    • Neoadjuvant chemotherapy is treatment given before surgery to shrink tumors.
    • Aim: To increase the chances of breast-conserving surgery.
    Q: What is Bevacizumab?
    • Bevacizumab is a monoclonal antibody that inhibits angiogenesis.
    • Aim: To reduce tumor blood supply and help chemotherapy work better.
    Q: What are the potential side effects of Neoadjuvant Chemotherapy?
    • Common side effects include:
      • Nausea and Vomiting
      • Fatigue
      • Hair Loss
      • Low Blood Cell Counts (anemia, neutropenia)
      • Mouth Sores
    • Less Common but Serious Effects:
      • Heart Problems
      • Liver Toxicity
    Q: What are the potential side effects of Bevacizumab?
    • Common side effects include:
      • High Blood Pressure
      • Fatigue
      • Gastrointestinal Perforation
      • Delayed Wound Healing
    • Less common but severe effects:
      • Risk of Hemorrhage
      • Cardiovascular Events
    Statistical Overview of Side Effects
    Side Effect Incidence Rate (%)
    Nausea 70
    Fatigue 65
    Hypertension (Bevacizumab) 30
    Heart Problems 5-10
    Gastrointestinal Perforation 1-5
    Mind Map of Side Effects
    – Neoadjuvant Chemotherapy – Nausea – Fatigue – Hair Loss – Blood Cell Decrease – Mouth Sores – Serious: Heart Problems, Liver Toxicity – Bevacizumab – High Blood Pressure – Fatigue – Gastrointestinal Issues – Serious: Hemorrhage Risk, Cardiovascular Events
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